伪石蒜硷(Pseudolycorine)是从我国产的植物水仙(Narcissus tazetta L.var.Chinensis Roen.)鳞茎中提取的生物硷之一,有抗病毒作用及抗大鼠Rauscher病毒性白血病作用,但未有关于抗实体瘤的实验材料报告。经由南京药学院中草药化学教研组及上海药物研究所植化室提取,我室进行抗瘤及药理研究。用该游离硷的生理盐水混悬液按10毫克/公斤/天腹腔注射7天,对大白鼠W～256抑制率为55～76.3％,该硷盐酸盐水溶液,按15～20毫克/公斤/天腹腔注射7夭,抑制率为 Pseudolycorine (Pseudolycorine) is one of the bio-derivatives extracted from the bulb of Narcissus tazetta L. var. Chinensis Roen. produced in China. It has antiviral effect and anti-rat Rauscher virus leukemia, but not Reports on experimental materials against solid tumors. It was extracted from the Institute of Chinese Herbal Chemistry of Nanjing Pharmaceutical University and the Institute of Shanghai Institute of Materia Medica. The anti-tumor and pharmacological studies were conducted in our laboratory. The free phlegm saline suspension was injected at 10 mg/kg/day intraperitoneally for 7 days. The inhibition rate of W~256 in rats was 55 to 76.3%. The aqueous solution of guanidine hydrochloride was 15 to 20 mg/kg. / Day intraperitoneal injection of 7 夭, inhibition rate