在人工牛黄中胆酸含量测定时，标准品和样品同时采用相应的试剂或水做空白，可以消除部颁标准ＷＳ_１－０２（Ｄ－０２）８８（简称部标法）因空白不一致而造成测定结果的正误差。改进后的方法简便，结果准确，回收率为９９．７９％和９９．４３％，制剂回收率为９９．９２％和１００．１４％。改进用两种方法，结果无显著差异。 When the content of bile acid in artificial bezoar is determined, the standard product and the sample are simultaneously blanked with the corresponding reagents or water, which can eliminate the measurement caused by the inconsistency of the blank in the ministry standard WS_1-02(D-02)88 (abbreviated as the landmark method). The positive error of the result. The improved method is simple and accurate. The recovery rate is 99.79% and 99.43%. The recovery rate of the preparation is 99.92% and 100.14%. There are no significant differences in the results using the two methods.