1.概况自从1980年国外首次引入牛胶原皮肤填充剂,软组织皮肤填充剂注射已成为脸部整形除皱临床常见的治疗手段。随着肉毒杆菌毒素除皱治疗技术、生物材料技术的进步及人们逐渐对微创手术的认可和需求,透明质酸类软组织皮肤填充剂脸部皱纹得到了快速发展。2003年到2004年美容除皱透明质酸类皮肤填充剂增长了660%。近年来正保持着快速稳定持续的增长。 1. Overview Since the introduction of bovine collagen skin filler in foreign countries for the first time in 1980, the injection of soft tissue dermal filler has become a common treatment for facial plastic surgery. With the treatment of botulinum toxin wrinkle removal, the progress of biomaterials technology and the gradual acceptance and demand of minimally invasive surgery, the facial wrinkles of hyaluronic soft tissue dermal filler have been rapidly developed. From 2003 to 2004, the cosmetic cleansing hyaluronic acid dermal filler increased by 660%. In recent years, it has maintained rapid, steady and sustained growth.