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(R)-2-羟基-4-苯基丁酸乙酯是血管紧张素转化酶抑制剂类(ACEI)药物的重要中间体.综述了其合成方法,重点介绍了最新的高效合成方法的研究进展.
(R) -2-hydroxy-4-phenylbutyrate is an important intermediate of angiotensin-converting enzyme inhibitors (ACEIs) .In this paper, the synthetic methods and the latest research on efficient synthetic methods are reviewed progress.