癫痫是神经系统的一种常见疾病,药物治疗是癫痫治疗的首选方法。由于癫痫病程长,患者常常需要长期服药甚至终身服药,药物长期服用的安全性是必须考虑的。有研究显示癫痫患者的骨折风险是普通人群的2~6倍,长期服用抗癫痫药物(AEDs)是导致骨折风险增加的独立危险因素。不同类型的AEDs对不同年龄阶段人群的骨代谢有不同的影响,应根据不同年龄选择合适的药物。如何预防骨折是癫痫专科医生应该关心的问题,应注意监测相关指标,防止骨折的发生。 Epilepsy is a common disease of the nervous system and drug treatment is the preferred method of treatment for epilepsy. Due to the long duration of epilepsy, patients often need long-term medication or even lifelong medication, long-term drug safety must be considered. Studies have shown that patients with epilepsy fracture risk is 2 to 6 times the general population, long-term use of antiepileptic drugs (AEDs) is an independent risk factor leading to increased fracture risk. Different types of AEDs have different effects on bone metabolism in different age groups, and appropriate drugs should be chosen according to age. How to prevent fractures is the epilepsy specialist should be concerned about the problem, should pay attention to monitoring the relevant indicators to prevent the occurrence of fractures.