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目的 了解不孕妇女下生殖道中病原体的感染情况。方法 A组 :对照组 ,2 76例正常健康育龄妇女。B组 :3 0 7例原发不孕女性患者。采用衣原体培养、支原体培养、淋病奈瑟菌培养和真菌培养 ,分别对 5 83例妇女宫颈分泌物进行沙眼衣原体(CT)、支原体 (UU)和淋病奈瑟菌 (NG)及念珠菌检测。结果 不孕妇女下生殖道沙眼衣原体 (CT)、支原体 (UU)、淋病奈瑟菌 (NG)及念珠菌阳性率分别为 15 3 1% (4 7/3 0 7) ,19 87% (61/3 0 7) ,11 0 7% (3 4/3 0 7)和 2 4 76% (76/3 0 7)。与对照组比较沙眼衣原体、支原体和淋病奈瑟菌阳性率差异有显著性意义 (χ2 =2 5 67,P <0 0 0 1;χ2 =3 3 88,P <0 0 0 1;χ2 =18 0 2 ,P <0 0 0 1) ,而两组念珠菌检出阳性率无显著性差异 (P >0 0 5 )。结论 原发不孕与女性下生殖道沙眼衣原体、支原体和淋病奈瑟菌感染密切相关 ,而与念珠菌感染关系不密切。
Objective To understand the infection of pathogens in lower genital tract of infertile women. Method A group: control group, 2 76 normal healthy women of childbearing age. Group B: 307 patients with primary infertile women. Chlamydia trachomatis (CT), mycoplasma (UU), Neisseria gonorrhoeae (NG) and Candida were tested on 5 83 cervical secretions of women using chlamydial culture, mycoplasma culture, Neisseria gonorrhoeae culture and fungal culture respectively. Results The positive rates of CT, UU, NG and Candida in the lower genital tract of infertile women were 15 3 1% (4 7/3 0 7) and 19 87% (61 / 3 0 7), 11 0 7% (3 4/3 0 7) and 2 4 76% (76/3 0 7). Compared with the control group, the positive rates of Chlamydia trachomatis, Mycoplasma and Neisseria gonorrhoeae were significantly different (χ2 = 2567, P <0.01; χ2 = 3388, P <0.01; χ2 = 18 0 2, P <0 0 0 1). There was no significant difference in the positive rate of Candida between the two groups (P> 0.05). Conclusions Primary infertility is closely related to genital C. trachomatis, Mycoplasma and Neisseria gonorrhoeae infection in female, but not to Candida infection.