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为了填充和修复良性骨肿瘤及瘤样病变刮除或切除术后遗留的骨缺损,作者自1990年5月~1996年5月采用经75%酒精浸泡贮存的同种异体胎儿骨移植治疗良性骨肿瘤及瘤样病变31例,取得了良好的效果。术后除5例发生体温变化,平均7天恢复正常体温,1例刀口浅表感染外,其余病例无明显不良反应。术后3周胎儿骨开始吸收,5周腔壁处有新骨生长影象,平均9个月肿瘤腔完全由新生骨代替。因此,作者认为胎儿骨具有制做及贮存方法简易、“爬行替代”作用快、骨诱导能力强、免疫排斥反应小等优点,是一种良好的植骨材料。
In order to fill and repair benign bone tumors and tumor-like lesions after curettage or resection of the remnants of bone defects, the author from May 1990 to May 1996 with 75% alcohol soaked embryo allograft bone transplantation for the treatment of benign bone Tumor and tumor-like lesions in 31 cases, and achieved good results. In addition to 5 cases of postoperative body temperature changes, an average of 7 days to return to normal body temperature, 1 case of superficial knife infection, the remaining cases no significant adverse reactions. Fetal bone began to be absorbed 3 weeks after operation, and new bone growth was observed at the 5-week cavity wall. The tumor cavity was completely replaced by new bone at 9 months. Therefore, the authors believe that fetal bone is a good bone graft material with the advantages of simple preparation and storage, fast acting of “crawling replacement”, strong osteoinduction ability and small immune rejection reaction.