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早在1929年,Drury等就已发现腺苷对心脏的作用,但直到1972年Bumstock才提出嘌呤能假说。目前研究表明,腺苷信号通路参与了体内多方面生理与病理过程。本文就腺苷及其受体在泌尿生殖系统的表达及作用机制作一综述。
As early as 1929, Drury et al. Had discovered the effect of adenosine on the heart, but it was not until 1972 that Bumstock proposed the purine hypothesis. Current research shows that adenosine signaling pathway involved in many aspects of the body’s physiological and pathological processes. This article reviews the expression of adenosine and its receptor in urogenital system and its mechanism of action.