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目的了解孕妇不同孕期血清铜、锌、钙、镁、铁元素的变化规律。方法 1 045名孕妇,根据怀孕不同分为3组,早孕组(孕周<16周)453例,中孕组(孕16～28周)546例,晚孕组(孕周>28周)46例;另选80名非孕妇女作为对照组。采用原子吸收分光光度法检测各组血铜、锌、钙、镁、铁元素含量,并进行比较。结果早、中晚孕组血铜含量均高于对照组(P<0.01);早、中孕组钙、锌、镁含量明显下降(P均<0.05);而早、中、晚孕组铁含量均缺乏(P<0.01)。结论铜元素随着孕周的增加而逐渐升高,血锌、钙、镁、铁元素则随着孕周的增加而逐渐降低;应加强孕期保健,监测各种元素在体内的变化。
Objective To understand the changes of serum copper, zinc, calcium, magnesium and iron in different pregnant women. Methods A total of 1,045 pregnant women were divided into 3 groups according to their pregnancy. There were 453 pregnant women (gestational age <16 weeks), 546 pregnant women (16 ~ 28 weeks pregnant), 466 pregnant women (gestational age> 28 weeks) 46 Cases; another 80 non-pregnant women as a control group. The contents of copper, zinc, calcium, magnesium and iron in each group were determined by atomic absorption spectrophotometry and compared. Results The levels of blood copper in the early and middle and late pregnancy groups were significantly higher than those in the control group (P <0.01). The contents of calcium, zinc and magnesium in the early and middle pregnancy groups were significantly decreased (P <0.05) Lack of content (P <0.01). Conclusions Copper increases gradually with the increase of gestational age. The levels of Zinc, Calcium, Magnesium and Iron decrease gradually with the increase of gestational age. Prenatal care should be strengthened and the changes of various elements in the body should be monitored.