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近年来,有关血小板生理功能及病理作用的研究取得了很大进展。抗血小板药已经作为一组有效药物开始在临床应用。一、血小板的功能1.粘附:即血小板粘贴于异物或血管内膜下组织表面。正常情况下,血小板在血管内沿着管壁缓缓流动,并不能粘附于管壁。内膜损伤时,血小板在该处增多,经过形态变化即粘附于暴露出来的胶原纤维和基底膜上。粘附的血小板随即被激活。这是止血或血栓形成的第一步。血小板粘附所伴发的改变是:(1)失
In recent years, great progress has been made in the research on the physiological functions and pathological effects of platelets. Antiplatelet drugs have started their clinical use as a group of effective drugs. First, the function of platelets 1. Adhesion: the platelet paste in foreign body or intima under the surface of the tissue. Under normal circumstances, platelets in the blood vessels along the wall slowly flowing, and can not adhere to the wall. Intimal injury, platelets in the area increased, after the morphological changes that adhere to the exposed collagen fibers and basement membrane. The adherent platelets are activated immediately. This is the first step in stopping bleeding or thrombosis. The changes associated with platelet adhesion are: (1) Loss