中西医结合治疗狼疮性肾炎优化方案的临床研究

来源 :中国伤残医学 | 被引量 : 0次 | 上传用户:linlijun002
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目的:观察与比较中西医结合方法治疗狼疮性肾炎患者的临床疗效。方法:采取回顾性的分析方法,筛选出符合入选条件的狼疮性肾炎患者,其中采用单纯西药治疗的有57例,采用中西药联合治疗的有56例,分析治疗结束时,2组患者的血生化指标、尿常规及免疫学指标,并加以比较。结果:与治疗前相比,2组患者治疗后24小时尿蛋白定量、肾功能、血沉等指标明显改善。中西药组患者治疗后24小时尿蛋白定量、血肌酐及尿素氮水平低于西药组,差异有统计学意义(P<0.05)结论:2组治疗方案均可改善患者肾功能。中西药联合应用在减轻尿蛋白、降低血肌酐及尿素氮水平的效果方面较单纯应用西药组更佳。 Objective: To observe and compare the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of patients with lupus nephritis. Methods: A retrospective analysis was conducted to screen out patients with lupus nephritis who met the inclusion criteria. Among them, 57 cases were treated with western medicine alone and 56 cases were treated with traditional Chinese and western medicine. At the end of treatment, the blood of 2 patients Biochemical indicators, urine and immunological indicators, and to be compared. Results: Compared with those before treatment, urinary protein, renal function, erythrocyte sedimentation rate and other indexes were significantly improved 24 hours after treatment in both groups. The levels of urinary protein, serum creatinine and blood urea nitrogen were lower in Western medicine group than those in western medicine group at 24 hours after treatment (P <0.05) .Conclusion: Both groups can improve renal function in patients. Combination of Chinese and Western medicine in reducing urinary protein, lower serum creatinine and urea nitrogen levels than the simple application of Western medicine group better.
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