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胰腺内、外分泌功能可经血液中内分泌及旁分泌作用而相互影响。目前认为雌激素可影响胰腺内外分泌功能,因而可能对胰腺癌也有作用。雌激素与胰酶合成:胰酶排泌受雌激素影响,应用雌激素后胰液成分显著改变,其中蛋白浓度降低,锌和重碳酸钠下降,淀粉酶、脂肪酸、胰组织内甘油三脂和总脂增加。细胞内雌激素的结合:体外实验表明雌激素与雌
The intra- and exocrine functions of the pancreas can be influenced by the endocrine and paracrine effects in the blood. It is currently believed that estrogen can affect the exocrine and exocrine functions of the pancreas, which may also have an effect on pancreatic cancer. Estrogen and pancreatic enzyme synthesis: Excretion of trypsin is affected by estrogen. After application of estrogen, the composition of the pancreatic juice is significantly changed, in which the protein concentration decreases, zinc and sodium bicarbonate drop, amylase, fatty acids, pancreatic tissue triglycerides and total. Increased fat. Intracellular Estrogen Binding: In Vitro Experiments Show Estrogen and Female