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目的 探讨安合素口服液的药理学作用。方法 安合素口服液以6.84g/kg及13.68g/kg剂量给予由环磷酰胺诱导的模型小鼠,采用脾细胞增殖试验、微核试验以及测定外周血白细胞总数作为观察指标。结果 该口服液可不同程度地拮抗由环磷酰胺诱导免疫功能低下、骨髓细胞的遗传损伤、外周血白细胞减少症。结论 提示安合素口服液具有扶正固本的作用。
Objective To investigate the pharmacological effects of Anshensu oral solution. Methods Anshen oral liquid was administered to cyclophosphamide-induced model mice at doses of 6.84 g/kg and 13.68 g/kg. Splenocyte proliferation assay, micronucleus test, and determination of the total number of white blood cells in the peripheral blood were used as observation indicators. Results The oral solution could antagonize the immunosuppression induced by cyclophosphamide, genetic damage of bone marrow cells, and leukopenia in peripheral blood. Conclusion It is suggested that Anshensu oral solution has the effect of strengthening the body.