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维生素D调节钙和磷吸收,促进骨骼的生长和重构。越来越多的研究证实,维生素D在高血压、肿瘤、自身免疫性疾病、2型糖尿病等疾病的发生和发展中起重要作用。研究发现,维生素D受体(VDR)广泛分布于卵巢、子宫、输卵管、宫颈、乳腺、睾丸、精子等生殖器官、组织与细胞中。关于维生素D的活性代谢产物的生理作用已进行了广泛研究,但其在人类生殖中的报道较少。现本文就维生素D缺乏对女性生殖系统功能的影响做一综述。
Vitamin D regulates calcium and phosphorus absorption and promotes bone growth and remodeling. More and more studies confirm that vitamin D plays an important role in the occurrence and development of diseases such as hypertension, cancer, autoimmune diseases and type 2 diabetes. The study found that vitamin D receptor (VDR) widely distributed in ovaries, uterus, fallopian tubes, cervix, breast, testis, sperm and other reproductive organs, tissues and cells. The physiological role of the active metabolite of vitamin D has been extensively studied, but it has been reported less in human reproduction. This article reviews the impact of vitamin D deficiency on female reproductive system function.