论文部分内容阅读
目的调查分析我国西部地区松果体区肿瘤治疗模式,为其临床路径的建立提供依据。方法回顾性分析我国西部地区9家三甲医院脑外、放疗科近8年松果体区肿瘤治疗资料,重点分析其手术、放射治疗的选择及治疗方法、步骤等。结果共收集219例,其中手术治疗58例,肿瘤全切除52例,肿瘤次全切6例;放射治疗196例:脑室-腹腔分流术和三脑室造瘘术后放疗99例、直接单纯放疗58例、手术切除加放射治疗39例。在放射治疗中,采用立体定向放射治疗153例、直线加速器放疗43例(其中先行诊断性放疗25例),其中常规分割全中枢照射放疗21例。结论脑室-腹腔分流术/三脑室造瘘术+放疗是松果体区肿瘤治疗的最多见模式,其次为肿瘤切除+放疗模式,放射治疗在照射方式与照射剂量方面差异巨大,提示松果体区肿瘤的治疗极不规范,建立松果体区肿瘤的诊治规范是极为重要和迫切的。
Objective To investigate and analyze the tumor treatment model of pineal region in the western part of our country and provide evidence for establishing its clinical pathway. Methods Retrospectively analyzed the data of tumor treatment of pineal region in the brain and radiotherapy department of 9 top three hospitals in western China, and analyzed the choice and treatment of the surgery and radiotherapy, the procedure and so on. Results A total of 219 cases were collected, of which 58 cases were treated surgically, 52 cases were completely excised and 6 cases were subtotally resected. Radiotherapy was performed in 196 cases: 99 cases were treated by ventricle-peritoneal shunt and 99% Cases, surgical resection plus radiotherapy in 39 cases. In radiotherapy, 153 cases were treated with stereotactic radiotherapy and 43 cases were treated with linear accelerator (including 25 cases with diagnostic radiotherapy), of which 21 cases were routinely divided into central-central radiation radiotherapy. Conclusions Ventricular-peritoneal shunt / triple ventrostomy + radiotherapy is the most common mode of tumor treatment in pineal region, followed by tumor resection + radiotherapy mode. Radiation therapy has great difference in irradiation mode and dose, suggesting that pineal gland District tumor treatment is very non-standard, the establishment of pineal tumor diagnosis and treatment of norm is extremely important and urgent.