在鄱阳湖洲岛型血吸虫病超重疫区，采用阳性病人选择性化疗措施，３年后居民感染率从３９．５７％下降到３０．６４％；肝肿率、巨大肝肿率和脾肿率分别下降了２６．９２％、９１．９２％和８３．６４％。肝、脾肿率，特别是巨大肝肿率随着年龄的增长而递增，４０岁达高峰。研究结果显示：选择性人群化疗可以有效地降低该病的流行强度和控制患病，但无法控制疾病的流行与传播。 In Poyang Lake Island schistosomiasis overweight epidemic area, the use of positive patients selective chemotherapy, 3 years after the inhabitant infection rate fell from 39.57% to 30.64%; hepatomegaly, macrocytosis and splenomegaly rate Decreased by 26.92%, 91.92% and 83.64% respectively. Liver, splenomegaly rate, especially the rate of huge hepatomegaly increased with age, peaked at the age of 40. The results show that: selective population chemotherapy can effectively reduce the epidemic intensity of the disease and control the disease, but can not control the spread of the disease.