Cardiac troponins in the elderly:interpretation of elevated levels

来源 :Journal of Geriatric Cardiology | 被引量 : 0次 | 上传用户:xjl121121
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Elderly patients with myocardial infarction commonly present with symptoms other than chest pain. The clinician evaluation of the elderly may rely on laboratory methods more so than in younger patients. Fortunately,advances in laboratory science have brought newer biomarkers of cardiac injury to the clinical arena including cardiac troponins I and T(cTnI,cTnT) . These regulatory components of the contractile apparatus are sensitive indicators of myocardial injury. Their central role in the current definition of acute myocardial infarction highlights their utility in the diagnosis of acute myocardial ischemic syndromes. The troponins are also released in some clinical situations where thrombotic complications of coronary artery disease and resultant acute myocardial infarction have not occurred. Examples of these conditions include conditions like myocarditis,pulmonary embolism,sepsis,and acute stroke. Elevated troponins in these conditions are thought to emanate from injured myocardial cells and in most circumstances have been associated with adverse outcomes. Interpretation of elevated troponin in the elderly requires consideration of other possible conditions. Elderly patients with myocardial infarction commonly present with symptoms other than chest pain. The clinician evaluation of the elderly may rely on laboratory methods more than in clinical patients These regulatory components of the contractile apparatus are sensitive indicators of myocardial injury. These regulatory components of the contractile apparatus are sensitive indicators of myocardial injury. The regulatory role of the contractile apparatus are sensitive indicators of myocardial injury. are also released in some clinical situations where thrombotic complications of coronary artery disease and genital myocardial infarction have not occurred. Examples of these conditions include conditions like myocarditis, pulmonary embolism, sepsis, and acute stroke. Elevated troponins in these conditions are thought to emanate from injured myocardial cells and in most cases have been associated with adverse outcomes. Interpretation of elevated troponin in the elderly requires not of possible other conditions.
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