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本文研究了交感神经阻断药胆碱二甲苯醚(TM10)及Bretylium对家免带神经的离体心房及离体兔耳的作用,在一定浓度下,两者均能取消交感神经兴奋的作用,对迷走神经在高浓度时也稍具有抑制作用;但对交感神经更具选择性,这种阻断作用都是可恢复的,对乙醯胆碱在有阿託品存在情况下的加速作用也能抑制,但对酪胺及苯丙胺均无对抗作用,却反增强之,在兔耳血管灌流的实验中,也得到相似的结果,胆碱二甲苯醚及Bretylitum能阻断
In this paper, we studied the effects of sympathectomy drugs TM10 and Bretylium on isolated atria and isolated rabbit auricles, and at a certain concentration, both of them can cancel the sympathetic excitement , The vagus nerve at a high concentration also slightly inhibitory effect; but more selective for the sympathetic, this blocking effect is recoverable, the role of acetylcholine in the presence of atropine accelerated role also Can inhibit, but tyramine and amphetamine no antagonism, but anti-enhanced, in the rabbit ear vascular perfusion experiments, also get similar results, chloralkyline and Bretylitum can block