论文部分内容阅读
目的 观察异丙酚对人工流产病人呼吸气体流速的影响,以期将异丙酚对呼吸的抑制程度进行量化描述。方法 择期行无痛人流术的早期妊娠病人40例,ASA Ⅰ级,异丙酚静脉麻醉。首次剂量为2.5 mg/kg,根据术中情况静脉追加30-50 mg。监测脉率及脉搏血氧饱和度。热线风速仪参数设定为:采样频率100 Hz,时间81.96 s。在麻醉前、后分别采样。观察每例病人麻醉前、后脉率、血氧饱和度、呼吸暂停发生率、及吸气、呼气相平均及气流最大速度、气体流量及动压、呼吸频率及平均每次吸气、呼气时间等呼吸力学相关指标。结果 与麻醉前比较,异丙酚麻醉后血氧饱和度下降(P<0.01),吸气、呼气相平均及气流最大速度、气体流量及动压下降(P<0.05),其中吸气相的改变尤其明显(P<0.01),呼吸频率增加(P<0.01),平均每次吸气、呼气时间缩短(P<0.01)。结论 异丙酚静脉麻醉后病人呼吸气流速度、流量及气体动压均降低,尤以吸气相更为明显。
Objective To observe the effect of propofol on the respiratory flow rate of induced abortion, and to quantitatively describe the degree of respiration of propofol. Methods Elective painless abortion in 40 cases of early pregnancy patients, ASA Ⅰ, propofol intravenous anesthesia. The first dose of 2.5 mg / kg, according to intraoperative venous additional 30-50 mg. Monitor pulse rate and pulse oximetry. Hot air anemometer parameters set as follows: Sampling frequency 100 Hz, time 81.96 s. Before anesthesia, after sampling. Before and after anesthesia in each patient observed pulse rate, oxygen saturation, the incidence of apnea, and inspiratory, expiratory average and maximum airflow speed, gas flow and dynamic pressure, respiratory rate and the average of each inhale, call Gas time and other respiratory mechanics related indicators. Results Compared with those before anesthesia, propofol anesthesia decreased the oxygen saturation (P <0.01), the average inspiratory and expiratory phases, the maximum airflow velocity, the gas flow rate and the dynamic pressure decreased (P <0.05) (P <0.01). The respiratory rate increased (P <0.01), and the average time of inspiration and expiration decreased (P <0.01). Conclusion Propofol intravenous anesthesia patients respiratory flow velocity, flow and gas dynamic pressure are reduced, especially the inspiratory phase is more obvious.