论文部分内容阅读
晶状体具有良好的透光性与适度的折光性,是一个近乎完美的视觉器官。它来源于表皮外胚叶,由外向内依次为晶状体囊、晶状体上皮、皮质及核,其中晶状体上皮细胞是整个晶状体的生命中枢,不仅分泌Ⅳ型胶原形成外层晶状体囊,并在赤道部衍化为纤维细胞,构成皮质与核;而且提供了晶状体代谢所需的全部能量。在长期高糖环境下,醛糖还原酶被激活,造成大量高渗性物质——山梨醇在细胞内堆积,引起皮质高度吸水膨胀;近年来还发现p糖-蛋白、细胞容积型氯离子通道和水通道蛋白也参与了糖性白内障渗透性膨胀期的发生发展。
The lens has a good light transmission and moderate refraction, is a near perfect visual organ. It is derived from the epidermal ectoderm, from the outside to the inside of the lens capsule, lens epithelium, cortex and nucleus, which is the lens of the lens epithelial cells of the life center, not only the secretion of type Ⅳ collagen formation of the outer lens capsule, and the evolution of the equator Fibroblasts, the cortex and nucleus; but also provides all the energy required for lens metabolism. In the long-term high sugar environment, aldose reductase is activated, resulting in a large number of hypertonic substances - sorbitol accumulation in the cell, causing cortical highly water swelling; in recent years also found p-glycoprotein, cell volume chloride channel And aquaporin are also involved in the development of the infiltration of glycocalyx infiltration.