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糖尿病是严重危害人类健康和生命的慢性代谢性疾病之一,随着人们生活水平的提高,其患病率和病死率急剧上升[1]。其中,心血管并发症是糖尿病患者最主要的死亡原因,约80%的糖尿病患者最终死于心血管疾病[2]。一项荟萃分析结果显示,糖尿病患者心血管并发症,包括冠状动脉疾病、心肌病等的发病率显著增加[3]。糖尿病患者的心血管并发症风险与血糖浓度密切相关,据统计,糖化血红蛋白每降低1%,心肌梗死的发生率同比降低
Diabetes is one of the chronic metabolic diseases that seriously endanger the health and life of human beings. With the improvement of people’s living standards, the prevalence and mortality rate have risen sharply [1]. Among them, cardiovascular complications are the leading cause of death in diabetic patients, and about 80% of diabetic patients eventually die of cardiovascular disease [2]. A meta-analysis showed a significant increase in the incidence of cardiovascular complications in diabetic patients, including coronary artery disease and cardiomyopathy [3]. Cardiovascular complications in patients with diabetes risk and blood glucose levels are closely related, according to statistics, every 1% reduction in HbA1c, the incidence of myocardial infarction decreased year on year