牙周炎的发病机制,自身免疫起一定作用。牙周炎发展的始动因素之一是有化脓性球菌的存在,使机体免疫反应降低。作者在疗养地用物理矿泉疗法综合治疗牙周炎,检查免疫学指标和机体抵抗力的变化,评定治疗效果。材料和方法用玫瑰花结试验测定 T 和 B 淋巴细胞数,测定对茶碱敏感的 T 细胞亚群,检查血清IgG、IgA 和 IgM 含量,用细菌变应原作白细胞溶解反应检查机体对细菌的过敏性,检查血清补体活性,用硝基四氮唑兰(NBT)还原反应检查中性白细胞活性。观察中度广泛性牙周炎50例,年龄22～ The pathogenesis of periodontitis, autoimmune play a role. One of the initiating factors of periodontitis development is the existence of pyogenic bacteria, so that the body’s immune response is reduced. The author in the convalescent therapy with physical spa treatment of periodontitis, check the immunological indicators and changes in body resistance, assessment of treatment. Materials and Methods The rosette test was used to determine the number of T and B lymphocytes, the theophylline-sensitive T cell subsets, the serum IgG, IgA and IgM contents were examined, and bacterial allergens were used for leukocyte lysis to check for bacterial allergy The serum complement activity was examined, and the neutrophil activity was examined by reduction with nitrotetrazitara (NBT). 50 cases of moderate periodontitis were observed, aged 22 ~