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目的:探讨注射用丹参联合穴位电刺激在预防老年消化道肿瘤PICC术后下肢深静脉血栓(LDVT)形成中的应用情况。方法:选取入医院行PICC术的老年消化道肿瘤患者144例作为研究对象,采用数字随机法将患者分对照组和观察组,对照组行下肢功能训练,观察组在对照组基础上静脉滴注丹参注射液联合穴位电刺激,观察两组血流变指标、凝血指标、股总静脉流速和股深静脉流速变化情况,记录DVT发生率。结果:观察组术后7天血流变指标[高切全血粘度(3.34±0.71)Pa·s、低切全血粘度(8.55±0.87)Pa·s、血浆粘度(1.32±0.12)Pa·s]均显著低于对照组,差异具有统计学意义(P<0.05)。观察组股总静脉流速[左侧(26.61±4.19)v/cm·s-1、右侧(26.08±3.69)v/cm·s-1]、股深静脉流速[左侧(18.87±5.79)v/cm·s-1、右侧18.28±4.43v/cm·s-1]均显著高于对照组,差异具有统计学意义(P<0.05)。观察组LDVT发生率为2.78%显著低于对照组16.67%,差异具有统计学意义(P<0.05)。结论:注射丹参联合穴位电刺激能够降低血液粘稠度,促使下肢静脉血循环,可降低老年消化道恶性肿瘤患者LDVT发生率。
Objective: To investigate the application of Salvia miltiorrhiza combined with acupoint electrical stimulation in the prevention of lower extremity deep vein thrombosis (LDVT) after PICC in senile gastrointestinal tumors. Methods: One hundred and forty-four elderly patients with gastrointestinal cancer undergoing PICC were enrolled in this study. The patients were divided into control group, observation group and control group by digital randomization method. The control group received intravenous drip Danshen injection combined with acupoint electrical stimulation, blood rheology indicators, coagulation index, total femoral vein flow and deep femoral vein flow velocity were observed, and the incidence of DVT was recorded. Results: The indexes of hemorrheology (high cut whole blood viscosity (3.34 ± 0.71) Pa · s, low cut whole blood viscosity (8.55 ± 0.87) Pa · s, plasma viscosity (1.32 ± 0.12) Pa · s] were significantly lower than the control group, the difference was statistically significant (P <0.05). The total femoral vein flow velocity (left (26.61 ± 4.19) v / cm · s-1, right (26.08 ± 3.69) v / cm · s-1] and deep venous flow [18.87 ± 5.79 v / cm · s-1, right side of 18.28 ± 4.43v / cm · s-1] were significantly higher than the control group, the difference was statistically significant (P <0.05). The incidence of LDVT in observation group was significantly lower than that in control group (2.78% vs 16.67%, P <0.05). Conclusion: Danshen injection combined with acupoint electrical stimulation can reduce blood viscosity and promote venous circulation in lower extremities, which can reduce the incidence of LDVT in elderly patients with gastrointestinal cancer.