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目的:探讨对晚期胃癌患者采用替吉奥胶囊单药联合放疗方法的临床治疗效果。方法:对我院接受检查和治疗的80例晚期胃癌患者入院资料进行分析,医护人员根据患者来我院治疗时间(单、双日)分为两组,每组共有40例患者。患者入院后,医护人员对患者进行常规检查,如患者的心肺功能、体温等。对照组患者采用一线治疗方案联合放疗,实验中患者口服替吉奥胶囊单药联合放疗,比较两组患者治疗效果等指标。结果:实验组患者总有效率为45%,高于对照组患者(总有效率为37.5%);两组患者治疗后产生的毒副反应主要以血液学毒性、肝功能损害、放射性胰腺炎等为主。实验组3-4级白细胞减少、1-2级转氨酶升高和3-4级恶心呕吐的发生率均低于对照组,且患者中没有出现肾脏毒性。结论:临床上,对晚期胃癌患者采用替吉奥胶囊单药联合放疗效果显著,患者治疗后并发症较少,能够有效的延长患者生命,值得推广使用。
Objective: To investigate the clinical effect of using Gejiu capsule combined with radiotherapy in patients with advanced gastric cancer. Methods: 80 cases of advanced gastric cancer admitted to our hospital were analyzed for admission data. The medical staff were divided into two groups according to the treatment time (single and double days) in our hospital. There were 40 patients in each group. After the patient is admitted to the hospital, the medical staff conducts regular examination of the patient, such as the patient’s cardiopulmonary function and body temperature. Patients in the control group were treated with first-line therapy combined with radiotherapy. Patients in the experiment were treated with oral administration of Teglio capsules alone and in combination with radiotherapy. The therapeutic effect was compared between the two groups. Results: The total effective rate of the experimental group was 45%, which was higher than that of the control group (the total effective rate was 37.5%). The toxic and side effects of the two groups were mainly hematological toxicity, hepatic dysfunction and radioactive pancreatitis Mainly. Grade 3-4 leukopenia, 1-2 grade aminotransferase increased and 3-4 grade nausea and vomiting were lower than the control group, and no renal toxicity in patients. Conclusions: Clinically, the effect of using TIGO capsules combined with radiotherapy for patients with advanced gastric cancer is remarkable. The patients have fewer complications after treatment, which can effectively prolong the life of patients and should be widely used.