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目的观察BP素对晚期胰腺癌患者的临床疗效。方法将40例胰腺癌患者分为BP素治疗组和对照组各20例,其中BP素治疗组每天用100mg BP素+100ml 0.9%氯化钠注射液静脉滴注,连用30d,对照组常规对症治疗。观察两组患者体重、生活质量、临床症状、瘤体大小、免疫功能、肿瘤标记物、不良反应情况。结果治疗后两组患者体重、生活质量、临床症状、瘤体大小、免疫功能差异均有统计学意义。结论 BP素治疗能够改善晚期胰腺癌患者的临床症状,有稳定瘤体、提高生活质量、保护免疫功能的作用。
Objective To observe the clinical effect of BP on patients with advanced pancreatic cancer. Methods Forty patients with pancreatic cancer were divided into two groups (n = 20 each). The patients in the control group received intravenous infusion of 100 mg BP + 100 ml 0.9% sodium chloride once daily for 30 days, treatment. Two groups of patients were observed weight, quality of life, clinical symptoms, tumor size, immune function, tumor markers, adverse reactions. Results After treatment, the weight, quality of life, clinical symptoms, tumor size and immune function of the two groups were statistically significant. Conclusion BP treatment can improve the clinical symptoms of patients with advanced pancreatic cancer, stabilize the tumor, improve the quality of life and protect the immune function.