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目的:研究中药汤剂参麦注射液的抗肿瘤作用和免疫调节作用。方法:将80例晚期非小细胞肺癌患者随机分治疗组(参麦注射液联合化疗)和对照组(单纯化疗),均治疗2个周期。结果:治疗组和对照组的有效率在统计学上有显著性差异(P<0.05)。在改善患者生活质量,提高免疫功能方面,两组比较差异均有显著性(P<0.05)。结论:参麦注射液能够提高晚期非小细胞肺癌患者化疗疗效,并且能增强机体免疫力,改善患者的生活质量,在一定程度上提高机体对化疗的耐受性。
Objective: To study the antitumor effect and immunomodulatory effect of Chinese herbal decoction Shenmai injection. Methods: Eighty patients with advanced non-small cell lung cancer were randomly divided into treatment group (Shenmai injection combined with chemotherapy) and control group (chemotherapy alone), both for 2 cycles. Results: There was a statistically significant difference in the effective rates between the treatment group and the control group (P <0.05). There was significant difference between the two groups in improving the quality of life of patients and improving the immune function (P <0.05). Conclusion: Shenmai injection can improve chemotherapy efficacy in patients with advanced non-small cell lung cancer, and can enhance the body immunity and improve the quality of life of patients, to a certain extent, improve the body’s tolerance to chemotherapy.