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目的:探讨经尿道膀胱肿瘤电切术(TURBT)后病理组织标本中有无肌层组织是否可以作为评价手术质量的指标。方法:回顾性分析2013年1月~2013年12月收治的339例行TURBT治疗的膀胱癌患者临床资料,并观察其病理组织切片,评价肿瘤的大小、数目、形态、位置、分期和分级与病理切片中是否存在肌层组织的关系,并评价是否存在肌层与肿瘤复发的关系。结果:339例患者中,病理组织切片中存在肌层组织的患者272例(80.24%)。单因素分析表明肿瘤分期、分级及大小与病理组织切片中有无肌层组织相关。Ta/T1期肿瘤病理组织切片中存在肌层和不存在肌层患者的复发率分别为30.00%和44.78%,P=0.003,差异具有统计学意义。结论:TURBT后病理组织切片中是否存在肌层与肿瘤的复发相关,从而可以作为评价TURBT手术质量的指标。该指标可指导术者更彻底切除肿瘤,降低肿瘤复发率,在非肌层浸润性膀胱癌诊治中具有重要临床价值。
Objective: To investigate whether the presence of myometrial tissue in pathological tissue specimens after transurethral resection of bladder tumor (TURBT) can be used as an index to evaluate the surgical quality. Methods: The clinical data of 339 bladder cancer patients treated with TURBT from January 2013 to December 2013 were retrospectively analyzed. The pathological sections were observed and the size, number, shape, location, stage and grade of tumor were evaluated. The presence or absence of muscularis tissue in the pathological section and evaluation of the relationship between the presence of myometrial and tumor recurrence. Results: Among the 339 patients, there were 272 cases (80.24%) of the patients with muscularis mucosa in pathological section. Univariate analysis showed that the tumor staging, grading and size were related to the presence or absence of myometrial tissue in the pathological section. The recurrence rates of patients with and without muscularis in the Ta / T1 tumor pathological section were 30.00% and 44.78%, respectively, P = 0.003, the difference was statistically significant. Conclusion: The presence of muscular layer in TURBT pathological section correlates with tumor recurrence, which can be used as an index to evaluate the quality of TURBT surgery. The index can guide the surgeon to more completely remove the tumor and reduce the recurrence rate of tumor, which has important clinical value in the diagnosis and treatment of non-muscle invasive bladder cancer.