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目的:探讨炎症性肠病(IBD)鉴别诊断的规范及相应的治疗措施,并观察治疗的效果。方法:选取2009年12月-2011年12月期间我院收治的162例炎症性肠病患者作为研究对象,将他们随机分为观察组和对照组。观察组的81例患者联合使用5-氨基水杨酸制剂(5-ASA)、糖皮质激素和中药直肠滴入进行治疗;对照组81例患者单独使用5-ASA和糖皮质激素等药物进行治疗。一个疗程后,对比治疗前后两组患者的血常规、尿常规及大便常规的变化情况。结果:观察组患者的临床症状全部消失,结肠镜检查黏膜大致正常者有46例,完全缓解率为56.8%,总有效率100%。对照组患者临床症状全部消失、结肠镜检查黏膜大致正常者有30例,完全缓解率为37%,总有效率为92.6%。结论:联合使用5-ASA、糖皮质激素与中药直肠滴入法治疗炎症性肠病效果显著,具有重要的临床应用价值。
Objective: To investigate the criteria for the differential diagnosis of inflammatory bowel disease (IBD) and the corresponding treatment measures, and observe the effect of treatment. Methods: A total of 162 inflammatory bowel disease patients admitted to our hospital from December 2009 to December 2011 were selected as study subjects, and randomly divided into observation group and control group. Eighty-one patients in the observation group were treated with 5-aminosalicylic acid preparation (5-ASA), corticosteroids and traditional Chinese medicine instillation. 81 patients in the control group were treated with drugs such as 5-ASA and glucocorticoids alone . After a course of treatment, before and after treatment in both groups of patients with blood, urine and stool routine changes. Results: The clinical symptoms of the observation group all disappeared. There were 46 cases with normal mucosa of colonoscopy. The complete remission rate was 56.8% and the total effective rate was 100%. The clinical symptoms of the control group all disappeared, colonoscopy mucosa generally normal in 30 cases, the complete remission rate was 37%, the total effective rate was 92.6%. Conclusion: The combination of 5-ASA, corticosteroids and traditional Chinese medicine rectal infusion method for the treatment of inflammatory bowel disease has a significant effect, which has important clinical value.