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目的探讨雾化吸入沙丁胺醇治疗慢性喘息型支气管炎的临床疗效。方法回顾性分析2009年1月-2010年12月在我院治疗的56例的慢性喘息型支气管炎患者的临床资料,随机分为两组对照组与治疗组各28例。对照组采用常规治疗,治疗组在常规治疗基础上加用雾化吸入沙丁胺醇治疗,疗程约2周,比较两组疗效和肺功能第1s用力呼气量占预计值百分比(FEV%)。结果治疗组有效率86.2%明显高于对照组的68.9%,差异有统计学意义(P<0.05);不良反应发生率对照组的35.7%高于治疗组的17.8%,差异有统计学意义(P<0.05);治疗组FEV%的改善率82.9%明显高于对照的32.9%,差异有统计学意义(P<0.05)。结论应用沙丁胺醇雾化治疗能明显改善慢性喘息型支气管炎患者的呼吸功能,副作用小,治疗效果好。
Objective To investigate the clinical efficacy of nebulized albuterol in the treatment of chronic asthmatic bronchitis. Methods The clinical data of 56 patients with chronic asthmatic bronchitis who were treated in our hospital from January 2009 to December 2010 were retrospectively analyzed. They were randomly divided into two groups: control group and treatment group, 28 cases each. The patients in the control group were treated with conventional therapy. The patients in the treatment group were treated with inhaled salbutamol on the basis of conventional therapy for about 2 weeks. The forced expiratory volume of 1 s was compared with the predicted value (FEV%). Results The effective rate of treatment group was 86.2%, which was significantly higher than that of control group (68.9%) (P <0.05). The incidence of adverse reactions in control group was 35.7% higher than that of treatment group (17.8%), the difference was statistically significant P <0.05). The improvement rate of FEV% in treatment group was significantly higher than that of control (82.9% vs 32.9%, P <0.05). Conclusion Salbutamol nebulization can significantly improve the respiratory function of patients with chronic asthmatic bronchitis, with fewer side effects and better therapeutic effect.