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目的:分析对尿毒症患者进行血液透析联合血液灌流治疗的临床效果。方法:将2016年1月至2016年12月在广东省佛山市高明区人民医院进行血液透析治疗的90例尿毒症患者作为研究对象。在2016年1~6月对本组患者进行血液透析治疗,在2016年7~12月对本组患者联合进行血液透析与血液灌流治疗。对比分析对本组患者进行血液透析联合血液灌流治疗前后其发生皮肤瘙痒的情况及血钙、血磷、血清甲状旁腺激素水平的变化情况。结果:与进行血液透析联合血液灌流治疗前相比,对本组患者进行血液透析联合血液灌流治疗后其中度皮肤瘙痒、重度皮肤瘙痒的发生率较低,差异有统计学意义(P<0.05)。与进行血液透析联合血液灌流治疗前相比,本组患者进行血液透析联合血液灌流治疗后其血磷、血清甲状旁腺激素的水平较低,差异有统计学意义(P<0.05)。结论:对尿毒症患者联合进行血液透析与血液灌流治疗能降低其皮肤瘙痒的发生率及血磷、血清甲状旁腺激素的水平。
Objective: To analyze the clinical effect of hemodialysis combined with hemoperfusion on uremic patients. Methods: From January 2016 to December 2016, 90 patients with uremia treated by hemodialysis in Gaoming District People’s Hospital of Foshan City, Guangdong Province were enrolled. In January 2016 to June this group of patients hemodialysis treatment, in July 2016 to December this group of patients combined hemodialysis and hemoperfusion treatment. Comparative analysis of this group of patients before and after hemodialysis hemoperfusion treatment of pruritus and its occurrence of serum calcium, phosphorus, serum parathyroid hormone levels change. Results: Compared with those before hemodialysis combined with hemoperfusion, the incidence of itching and severe pruritus in patients with moderate to severe skin pruritus after hemodialysis combined with hemoperfusion was lower than that before hemodialysis combined with hemoperfusion. The difference was statistically significant (P <0.05). Compared with those before hemodialysis combined with hemoperfusion, the levels of serum phosphorus and serum parathyroid hormone in patients undergoing hemodialysis combined with hemoperfusion were significantly lower (P <0.05). Conclusion: The combination of hemodialysis and hemoperfusion in patients with uremia can reduce the incidence of pruritus and the levels of serum phosphorus and serum parathyroid hormone.