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目的观察孟鲁司特钠联合脱敏治疗儿童过敏性紫癜的疗效。方法选择2009年6月—2013年4月在我院儿科住院治疗的符合过敏性紫癜诊断标准患儿30例,随机分对照组12例和治疗组18例,对照组予常规治疗,治疗组在常规治疗基础上加用孟鲁司特钠联合脱敏治疗,持续治疗2个月。结果治疗组总有效率88.9%,对照组总有效率58.3%,二组患儿临床疗效对比,差异有统计学意义(P<0.05)。结论孟鲁司特钠联合脱敏治疗儿童过敏性紫癜是有效且安全的方法。家长易接受,值得临床推广。
Objective To observe the efficacy of montelukast combined with desensitization in the treatment of Henoch-Schonlein purpura in children. Methods Thirty children with allergic purpura diagnosed in pediatric department of our hospital from June 2009 to April 2013 were randomly divided into control group (n = 12) and treatment group (n = 18). The control group On the basis of conventional treatment with montelukast combined with desensitization treatment, continuous treatment for 2 months. Results The total effective rate was 88.9% in the treatment group and 58.3% in the control group. The clinical efficacy of the two groups was statistically significant (P <0.05). Conclusion Montelukast combined with desensitization is an effective and safe method for the treatment of Henoch-Schonlein purpura in children. Parents easy to accept, it is worth clinical promotion.