以苯乙烯、五氯化磷、无水乙醇等为原料,通过加成、酯化等反应合成了苯乙烯基膦酸二乙酯,讨论了产率的影响因素。研究表明:在干燥情况下,膦酰氯中间体与无水乙醇的摩尔比为1∶2.4,膦酰氯中间体与缚酸剂吡啶的摩尔比为1∶1.9时,产物产率可达92.5%,并通过元素分析、红外吸收光谱和1 H核磁共振波谱分析确定了目标产物结构。 Styrene, phosphorus pentachloride and anhydrous ethanol were used as raw materials to synthesize diethyl styrylphosphonate through addition reaction and esterification reaction, and the influencing factors of the yield were discussed. The results showed that the molar ratio of phosphonochlorid intermediate to anhydrous ethanol was 1: 2.4 and the molar ratio of phosphonic acid chloride intermediate and acid-binding pyridine was 1: 1.9, the product yield could reach 92.5% The structure of the target product was confirmed by elemental analysis, IR absorption and 1 H NMR spectroscopy.