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目的观察阿维A联合克拉霉素治疗多发性尖锐湿疣的临床疗效及安全性。方法治疗组38例,用CO2激光祛除疣体后口服阿维A30～40mg/d,共4周,克拉霉素0.5mg/d,共14天;对照组35例仅CO2激光治疗,比较两组疗效。结果治疗组复发4例,复发率10.53%;对照组复发17例,复发率48.57%,两组复发率差异有统计学意义(P<0.01)。结论阿维A联合克拉霉素可有效地抑制多发性尖锐湿疣的复发。
Objective To observe the clinical efficacy and safety of combination of acitretin and clarithromycin in the treatment of multiple condyloma acuminatum. Methods 38 cases of treatment group, CO2 laser wart after oral administration of Avastin A30 ~ 40mg / d, a total of 4 weeks, clarithromycin 0.5mg / d, a total of 14 days; control group 35 cases of CO2 laser treatment only, compared two groups Efficacy. Results The recurrence rate was 10.53% in the treatment group (4 cases) and 17 cases (48.57%) in the control group. There was significant difference between the two groups (P <0.01). Conclusions Avastin combined with clarithromycin can effectively inhibit the recurrence of multiple condyloma acuminatum.