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为了解氯丁二烯(CBD)的致癌性,对氯丁橡胶车间进行了20年回顾性调查,时间自1970年1月1日至1989年12月31日。调查结果,20年全厂平均死亡率为3.42‰,CBD工人平均死亡率为2.59‰,差别无显著意义(P>0.05)。CBD工人癌症死亡率为47.16/10万,与全厂癌症死亡率比较以及与青岛市居民癌症死亡率比较,差别均无显著意义。CBD工人与非CBD工人癌症死亡率比较,CBD工人不比非CBD工人高。CBD工人发癌年令平均为46.25±5.75(岁),非CBD工人平均为53.54±1.75(岁),差别无统计学意义(P>0.2)。提示CBD无明确的致癌作用。
To understand the carcinogenicity of chlorbutadiene (CBD), a 20-year retrospective survey of the neoprene workshop took place from January 1, 1970 to December 31, 1989. According to the survey results, the average mortality rate of the whole plant in 20 years was 3.42 ‰, while the average death rate of CBD workers was 2.59 ‰, with no significant difference (P> 0.05). The death rate of cancer in CBD workers was 47.16 / 100 000, which was not significantly different from the cancer mortality rate of the whole factory and the cancer mortality rate of Qingdao residents. CBD workers have a higher rate of cancer death than non-CBD workers than non-CBD workers. The average annual incidence of cancers in CBD workers was 46.25 ± 5.75 (years), and that of non-CBD workers was 53.54 ± 1.75 (years), with no significant difference (P> 0.2). Tip CBD no specific carcinogenic effects.