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目的:回顾性分析肺隐球菌病的临床及CT表现,探讨不同免疫状态对本病的影响。材料和方法:经病理证实的肺隐球菌病23例,男性13例,女性10例,其中儿童3例,平均年龄33.2岁(5-50岁),其中免疫功能低下者5例。CT扫描采用10mm层厚连续观察,其中2例做1.5mm层厚的HRCT。结果:成人正常免疫功能组患者临床症状较轻而CT表现较为明显,CT上以多发结节33.3%(5/15)、团块影33.3%(5/15)和片状渗出影27.1%(4/15)多见;成人免疫损害者和儿童则多为片状渗出影,分别为80%(4/5)和66.6%(2/3)。结论:肺隐球菌病CT表现多样,无特异性。病变多见于两下肺,正常免疫成人多见多发结节灶、团块和片状渗出影,而成人免疫损害者和儿童则以渗出影更多见,确诊有赖于病理学检查。
Objective: To retrospectively analyze the clinical and CT manifestations of pulmonary cryptococcosis and explore the influence of different immune states on this disease. MATERIALS AND METHODS: Twenty-three cases of pulmonary cryptococcosis were confirmed by pathology, including 13 males and 10 females, including 3 children (average age 33.2 years old (5-50 years old) and 5 cases with immunocompromised persons. CT scan using continuous observation of 10mm layer thickness, 2 cases of 1.5mm thickness HRCT. Results: The patients with normal immune function group had less clinical symptoms and more obvious CT findings. Multiple nodules were found in 33.3% (5/15), 33.3% (5/15) and 27.1% (4/15) were more common. Adult immunocompromised children and children were mostly exudative patches, which were 80% (4/5) and 66.6% (2/3), respectively. Conclusion: CT findings of pulmonary cryptococcosis are diverse and unspecific. Lesions more common in the lower lungs, multiple immunocompromised adults more common nodules, lumps and exudative film, and adult immunocompromised children and exudative shadow Zeyi more see the diagnosis depends on pathological examination.