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自1979年世界卫生组织首次将妊娠糖尿病作为糖尿病的一大亚型独立划分出来至今的30年间,妊娠糖尿病患病率不断增加,其对母婴健康的影响巨大,值得密切关注。妊娠糖尿病的病理机制可能与妊娠期间胰岛素抵抗加剧,以及胰岛素信号转递过程中多个环节受损有关,尚需更多的探索。为了保证母婴健康,对妊娠糖尿病的临床与基础研究仍需进一步加强。
Since 1979, the first time that WHO independently classified gestational diabetes as a major subtype of diabetes, the prevalence of gestational diabetes mellitus has been increasing over the past 30 years. The impact on maternal and child health is huge and deserves close attention. The pathological mechanism of gestational diabetes mellitus may be related to the intensification of insulin resistance during pregnancy, as well as the impairment of insulin signaling in the process of multiple links, still need more exploration. In order to ensure maternal and child health, clinical and basic research on gestational diabetes still need to be further strengthened.