论文部分内容阅读
洋地黄应用于心力衰竭的治疗已有200余年历史,迄今仍为一种可靠的增强心肌正性收缩能药物。由于此类药物治疗量与中毒量十分接近,加之患者对药物的吸收、代谢、排泄常受多种因素影响,因而测定患者血清洋地黄药物浓度,有助于调整服药剂量,防止中毒发生。在地高辛放射免疫分析法应用之前,曾报导过多种测定技术,但这些方法测定所需时间长,方法繁锁,特异性及灵敏度不高,因而限制了其临床应用。地高辛放射免疫测定则具有快速,灵敏度高,特异性强的特点,故有很大的临床实用价值。我院自1978年12月至1979年4
Digitalis has been used in the treatment of heart failure for more than 200 years and is still a reliable drug for enhancing positive myocardial contractility. Because of such drugs and toxic dose is very close, coupled with the patient’s absorption of drugs, metabolism, excretion often affected by many factors, so the determination of serum digitalis drug concentration, help adjust the dose, to prevent poisoning. Prior to the application of digoxin radioimmunoassay, a variety of assay techniques were reported, but these assays are time-consuming, cumbersome, cumbersome, and poorly-characterized, and therefore less sensitive, limiting their clinical utility. Digoxin radioimmunoassay has the characteristics of rapidity, high sensitivity and strong specificity, so it has great clinical practical value. Our hospital from December 1978 to 1979 4