论文部分内容阅读
目的探讨脊柱椎旁肌松解术治疗早期强直性脊柱炎的临床效果。方法对240例符合强直性脊柱炎(ankylosing spondylitis,AS)诊断标准的活动期患者,手术剥离腰2、3椎体后方的多裂肌在棘突、乳突及横突上的止点,达到松解胸腰段及腰骶段椎旁肌的目的。分别于术前、术后2、6、12、24周、1年、2年,观察C反应蛋白(CRP)、红细胞沉降率(ESR)炎症指标,同时对AS病情活动性指数(BASDAI)、AS功能指数(BASFI)、AS测量指数(BASMI)、AS健康综合指数(BAS-G)进行评估,最终评价患者满意率。结果所有患者手术顺利,无并发症发生。术后随访2年,CRP、ESR、BASDAI、BASFI和BAS-G一直维持在平稳水平,患者评价优良率86.3%。结论脊柱椎旁肌松解术治疗早期强直性脊柱炎效果显著,可有效降低炎症指标,缓解腰背疼痛、晨僵等症状,值得临床推广应用。
Objective To investigate the clinical effect of paravertebral muscle lysis on early ankylosing spondylitis. Methods 240 active patients with ankylosing spondylitis (AS) criteria were involved in the surgical dissection of the slippage of the spinous process, mastoid process and transverse process in the back of the lumbar 2 and 3 vertebrae Loosen the thoracolumbar and lumbosacral paraspinal muscle purposes. The indexes of inflammatory response of CRP and ESR were observed at preoperative, postoperative 2, 6, 12, 24 weeks, 1 year and 2 years respectively. BASDAI, BASFI, BASMI and BAS-G were used to evaluate the patients’ satisfaction rate. Results All patients underwent a successful operation with no complications. The patients were followed up for 2 years. CRP, ESR, BASDAI, BASFI and BAS-G were maintained at a stable level. The rate of excellent and good patients was 86.3%. Conclusions The treatment of ankylosing spondylitis by paravertebral muscle lysis in the spine has a significant effect, which can effectively reduce the inflammation index and alleviate the symptoms such as back pain and morning stiffness, which is worthy of clinical application.