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目的探讨丹参注射液联合美沙拉嗪治疗溃疡性结肠炎(UC)的疗效。方法选取2013年1月至2016年3月UC患者60例,将其随机分为两组,每组30例。对照组口服美沙拉嗪,观察组加用丹参注射液治疗。比较两组总有效率、Mayo评分、血沉(ESR)、血清C-反应蛋白(CRP)水平。结果观察组总有效率为93.3%(28/30),高于对照组的80.0%(24/30),差异有统计学意义(P<0.05)。治疗后两组患者Mayo评分、ESR、CRP均下降,且观察组低于对照组(P<0.05)。结论丹参注射液联合美沙拉嗪治疗UC能提高临床疗效,减轻炎性反应,值得临床推广。
Objective To investigate the curative effect of salvia miltiorrhiza injection combined with mesalazine in the treatment of ulcerative colitis (UC). Methods Sixty patients with UC were selected from January 2013 to March 2016, and were randomly divided into two groups of 30 patients. The control group oral mesalamine, the observation group plus Salvia injection treatment. The total effective rate, Mayo score, erythrocyte sedimentation rate (ESR) and serum C-reactive protein (CRP) levels were compared between the two groups. Results The total effective rate in the observation group was 93.3% (28/30), which was higher than that in the control group (80.0%, 24/30). The difference was statistically significant (P <0.05). After treatment, Mayo score, ESR and CRP decreased in both groups, and the observation group was lower than the control group (P <0.05). Conclusion Salvia miltiorrhiza injection combined with mesalazine in the treatment of UC can improve the clinical efficacy and reduce the inflammatory response, it is worth clinical promotion.