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诊断酶学在临床上的应用开始于本世纪初。1908年Wohlgemuth叙述了急性胰腺炎患者血清与尿中淀粉酶活性增高后,有关方面的研究逐渐增多,1954年La Due等报导心肌梗塞与肝脏病患者血清谷-草转氨酶活性升高是由于细胞受损,细胞内酶释放到血
Diagnostic enzymes in the clinical application began in the beginning of this century. 1908 Wohlgemuth recounts the serum and urinary amylase activity in patients with acute pancreatitis increased, the research has gradually increased, La Due et al reported in 1954, myocardial infarction and liver disease, serum glutamic-aspartate aminotransferase activity increased due to cellular receptors Loss, release of intracellular enzymes into the blood