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长春地辛(Vindesine,VDS,商品名西艾克)是长春花碱的衍生物。该药在动物实验中的抗瘤谱较长春新碱(VCR)及长春花碱(VLB)广,骨髓抑制低于VLB,神经毒性低于VCR[1]。我院自1994年10月至1996年3月试用杭州民生药厂生产的VDS,对sl例恶性肿瘤患者进行临床疗效及毒性作用观
Vindesine (VDS, trade name Xiaike) is a derivative of vinblastine. The anti-tumor spectrum of the drug in animal experiments was wider than vincristine (VCR) and vinblastine (VLB), and myelosuppression was lower than VLB. Neurotoxicity was lower than that of VCR [1]. The VDS produced by Hangzhou Minsheng Pharmaceutical Factory was tried in our hospital from October 1994 to March 1996, and the clinical efficacy and toxicity of the patients with malignant tumors were evaluated