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目的探讨影响老年腔隙性脑梗死患者认知功能障碍的危险因素并对其进行分析。方法选择2013年1月—2015年1月收治的60例老年腔隙性脑梗死患者作为观察组,并选择同期在神经内科住院的非腔隙性脑梗死患者60例作为对照组,两组患者均采用蒙特利尔认知功能量表进行认知功能障碍评估,分别对比两组患者的认知功能障碍以及观察组患者1年后认知功能Logistic回归分析。结果观察组患者在视空间与执行功能、语言以及延迟回忆方面与对照组患者有统计学差异,在命名、注意力、定向以及抽象方面无统计学意义;高脂血症与糖尿病是是引起老年腔隙性脑梗死患者认知功能障碍的主要危险因素。结论多数老年腔隙性脑梗死患者存在认知功能障碍,且高脂血症与糖尿病是引起老年腔隙性脑梗死患者认知功能障碍的主要危险因素。
Objective To explore and analyze the risk factors of cognitive dysfunction in elderly patients with lacunar infarction. Methods Sixty elderly patients with lacunar infarction admitted from January 2013 to January 2015 were selected as the observation group and 60 patients with non-lacunar cerebral infarction hospitalized in neurology department during the same period were selected as the control group. Two groups of patients Cognitive dysfunction assessment was performed using the Montreal Cognitive Function Scale, and cognitive impairment was compared between two groups of patients and Logistic regression analysis of cognitive function after 1 year in the observation group. Results The observation group had statistically significant differences in the spatial and executive functions, language and delayed recall compared with the control group patients, and there was no statistical significance in naming, attention, orientation and abstraction; hyperlipidemia and diabetes were the causes of senile Main risk factors of cognitive dysfunction in patients with lacunar infarction. Conclusion Most elderly patients with lacunar infarction have cognitive dysfunction, and hyperlipidemia and diabetes are the major risk factors of cognitive impairment in elderly patients with lacunar infarction.