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山东省 1999年共报告麻疹疑似病例 1776例 ,采集血清标本 86 1份 ,采集率为 48 48%。采用酶联免疫吸附试验 (ELISA)捕获法检测麻疹、风疹IgM抗体 ,阳性率分别为 5 9 12 % (5 0 9/ 86 1)和 10 34% (89/ 86 1) ,两者全部阴性者占 30 5 4% (2 6 3/ 86 1)。1337例麻疹暴发疑似病例 ,麻疹、风疹IgM抗体阳性率分别为 5 8 81% (32 7/ 5 5 6 )和 14 5 7% (81/ 5 5 6 ) ;439例散发疑似病例分别为 5 9 6 7% (182 / 30 5 )、2 6 2 % (8/ 30 5 )。首次在 1例典型麻疹确诊病例的咽拭子标本中分离到 1株麻疹野病毒株。ELISA捕获法检测IgM抗体用于麻疹的血清学早期诊断敏感性较高 ,其结果与血清标本采集时间及麻疹疑似病例的最终分类有很大的关系
Shandong Province in 1999 reported a total of 1776 cases of suspected measles cases, collected 861 serum samples collected 48 48%. Measles and rubella IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA) capture assay. The positive rates were 59 12% (5 0 9/86 1) and 10 34% (89 861) respectively, both of which were negative Accounting for 30 5 4% (2 6 3/86 1). The positive rates of measles and rubella IgM antibodies in the 1337 measles cases were 58 81% (32/7/5 5 6) and 145 7% (81/5 56) respectively. The suspicious cases of 439 cases were 59 6 7% (182/305), 26 62% (8/305). For the first time, a wild measles virus strain was isolated from one throat swab specimen of a typical measles case. ELISA capture detection of IgM antibodies for the early diagnosis of serological high sensitivity of measles, the results of serum samples collected and the final classification of suspected cases of measles have a great relationship