Diseases of cultured animal and environmental pollution are very important problems in aquaculture. The use of probiotics in aquaculture has more advantages than the use of antibiotics and chemicals in aquaculture. This review introduces the use and mechanisms of the probiotics in aquaculture. Diseases of cultured animal and environmental pollution are very important problems in aquaculture. The use of probiotics in aquaculture has more advantages than the use of antibiotics and chemicals in aquaculture. This review introduces the use and mechanisms of the probiotics in aquaculture.