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离子液体阴阳离子的可设计性使其具有可控溶解性、独特表面活性、高热稳定性、增强的生物利用率和生物活性,这些特点使离子液体在消除同质多晶现象、改变药物传输模式及可包含传统药物组分等方面具有优势,成为当前离子液体研究领域的热点之一。本文对离子液体在医药领域的应用做了全面的阐述,主要介绍了近十年来离子液体在活性药物组分、抗菌剂及除草剂方面的成果,探讨了当前存在的问题及研究方向,并对其应用做了展望。
The designability of anionic and cationic cations provides them with controlled solubility, unique surface activity, high thermal stability, enhanced bioavailability, and biological activity that have made ionic liquids to eliminate polymorphism and alter drug delivery patterns And can contain traditional drug components, etc., has become one of the hot spots in the field of ionic liquid research. This paper describes the application of ionic liquids in the field of medicine in detail, mainly introduces the achievements of ionic liquids in active pharmaceutical ingredients, antibacterial agents and herbicides in recent ten years, discusses the existing problems and research directions, Its application prospects.