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目的 了解肺结核病人院内下呼吸道感染的临床流行情况及其相关危险因素。方法 对 1 998年 1月~ 1 999年 1 2月实际出院的肺结核病人中符合院内下呼吸道感染者逐一填写医院感染病例登记表 ,对表内资料进行回顾性分析。结果 1 肺结核病人院内下呼吸道感染发生率 4 .9%。高危人群为伴有慢性肺部疾患的老年人、肺部以纤维空洞、支气管扩张、肺不张为主要病理损害的肺结核患者。相关危险因素为住院时间长、反复住院、重症结核病所致营养状态低下、大量长期使用广谱抗生素。 2 铜绿假单孢菌及克雷伯氏杆菌属是本院下呼吸道感染的主要致病菌 ,且合并真菌感染率高 ( 48 2 % )。结论 结核病人院内下呼吸道感染是一个值得关注的问题。
Objective To understand the prevalence and related risk factors of nosocomial lower respiratory tract infection in pulmonary tuberculosis patients. Methods From January 1998 to January 1999, the actual hospital discharge of pulmonary tuberculosis patients who met the hospital’s lower respiratory tract infections were completed one by one to complete the hospital infection registration form, and the internal data were retrospectively analyzed. Results 1 The incidence of lower respiratory tract infections in patients with tuberculosis was 4.9%. High-risk groups were elderly patients with chronic lung disease, pulmonary tuberculosis patients with fiber holes, bronchiectasis, and atelectasis as the main pathological lesions. The related risk factors are long hospital stay, repeated hospitalization, low nutritional status caused by severe tuberculosis, and long-term use of broad-spectrum antibiotics. 2 Pseudomonas aeruginosa and Klebsiella spp. are the main pathogens of lower respiratory tract infection in this hospital, and the combined fungal infection rate is high ( 482 2% ). Conclusion The lower respiratory tract infection in TB patients is a matter of concern.