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目的分析糖耐量减退并发尿路感染患者的血清钙浓度,评价血清钙浓度在此类患者治疗前后的检测价值。方法收集2013年1月到2016年7月间张家港市第一人民医院继发尿路感染患者的病历资料,从中筛选出符合研究要求的患者166例,其中非糖尿病患者57例,糖耐量减退患者64例,糖尿病患者45例,记录各组患者的血清钙检测结果进行统计学分析。结果糖耐量减退并发尿路感染组患者入院时血清钙与非糖尿病组及糖尿病组患者比较差异均无统计学意义(mmol/L:2.26±0.19比2.33±0.31、2.28±0.17,P均>0.05);尿路感染时糖耐量减退组和糖尿病组血清钙水平均比非糖尿病组明显降低,差异均有统计学意义(mmol/L:1.99±0.19、2.08±0.15比2.17±0.15,P均<0.05);糖耐量减退组患者出院好转时血清钙与非糖尿病组及糖尿病组患者比较差异均无统计学意义(mmol/L:2.20±0.18比2.27±0.13、2.21±0.11,P均>0.05)。除非糖尿病患者组外,糖耐量减退组、糖尿病组患者尿路感染时血清钙与入院时比较均明显降低,差异均有统计学意义(mmol/L:1.99±0.19比2.26±0.19,2.08±0.15比2.28±0.17,P均<0.05);出院好转时3组血清钙均比感染时明显升高,差异均有统计学意义(mmol/L:2.27±0.13、2.20±0.18、2.21±0.11比2.17±0.25、1.99±0.19、2.08±0.15,P均<0.05);3组患者入院时血清钙与出院好转时比较均无明显差异(mmol/L:2.33±0.31、2.26±0.19、2.28±0.17比2.27±0.13、2.20±0.18、2.21±0.11,P均>0.05)。结论血清钙在糖耐量减退患者并发尿路感染时显著降低,检测值的上升有助于临床医生对疾病的预后做早期判断。
Objective To analyze the serum calcium concentration in patients with impaired glucose tolerance and urinary tract infection and evaluate the serum calcium concentration before and after treatment. Methods A total of 166 patients with urinary tract infection were collected from the First People’s Hospital of Zhangjiagang from January 2013 to July 2016, of which 166 patients were eligible for the study. Among them, 57 were non-diabetic and those with impaired glucose tolerance 64 cases, 45 cases of diabetic patients, all patients were recorded serum calcium test results were statistically analyzed. Results There were no significant differences in the serum calcium levels between the patients with and without urinary tract infection and those without diabetes mellitus (mmol / L: 2.26 ± 0.19 vs 2.33 ± 0.31,2.28 ± 0.17, P> 0.05) ); Urinary tract infection with impaired glucose tolerance group and diabetic group serum calcium levels were significantly lower than non-diabetic group, the differences were statistically significant (mmol / L: 1.99 ± 0.19, 2.08 ± 0.15 vs. 2.17 ± 0.15, P < 0.05). There was no significant difference between the patients with and without diabetes mellitus (P <0.05) in patients with impaired glucose tolerance when the patients were discharged from the hospital. The difference was not statistically significant (mmol / L: 2.20 ± 0.18 vs 2.27 ± 0.13,2.21 ± 0.11, P all> 0.05) . The levels of serum calcium in patients with impaired glucose tolerance and diabetes mellitus were significantly lower than those of patients admitted to hospital except diabetic group (mmol / L: 1.99 ± 0.19 vs 2.26 ± 0.19, 2.08 ± 0.15 (2.28 ± 0.17, P <0.05). Serum Ca2 + levels in 3 groups were significantly higher than those in control group at discharge improvement (mmol / L: 2.27 ± 0.13,2.20 ± 0.18,2.21 ± 0.11 vs 2.17 ± 0.25,1.99 ± 0.19,2.08 ± 0.15, P <0.05). There was no significant difference in the serum calcium between the three groups when hospitalized (mmol / L: 2.33 ± 0.31, 2.26 ± 0.19, 2.28 ± 0.17 2.27 ± 0.13,2.20 ± 0.18,2.21 ± 0.11, P> 0.05). Conclusions Serum calcium is significantly decreased in patients with impaired glucose tolerance and urinary tract infection. The increase of the measured value may help clinicians make an early judgment on the prognosis of the disease.