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目的 分析血液透析治疗患者的护理需求?并发症发生情况，评价集束化护理干预预防导管相关血流感染(CRBSI)的价值?方法 选择我院2019 年3 月至2020 年3 月接受血液透析治疗的患者110 例，采取随机数表法分为对照组?观察组?对照组(n=55)患者采取血液透析常规护理，观察组(n=55)患者采取集束化护理干预，比较两组患者的护理效果?结果 观察组CRBSI 发生率为5.45%，低于对照组的20.00%(P < 0.05);观察组总满意度为96.36%，高于对照组的72.72%(P < 0.05);“,”Objective To analyze the nursing needs and complications of hemodialysis patients， and to evaluate the value of clustered nursing intervention to prevent catheter-related bloodstream infection (CRBSI). Methods Select the 110 patients treated by hemodialysis in our hospital from March 2019 to March 2020， and divided into the control group and the observation group by random number table method. Patients in the control group (n=55) received routine hemodialysis care， and patients in the observation group (n=55) received cluster nursing intervention， to compare the nursing effects of the two groups of hemodialysis patients. Results Comparing the incidence of CRBSI， the incidence of observation group was 5.45% lower than 20.00% of control group (P <0.05);compared with nursing satisfaction， the total satisfaction of observation group was 96.36% higher than 72.72% of control group (P <0.05);comparing the time of intervening catheterization， CRBSI duration， and hospital stay， the observation group took significantly shorter time than the control group (P <0.05);comparison of the CRBSI occurrence time between groups， the observation group took longer than the control group (P <0.05). Conclusion The risk of CRBSI complications in hemodialysis patients is higher. Strengthening the clustered nursing intervention can effectively prevent and prolong the occurrence of CRBSI and speed up the recovery of CRBSI patients. The nursing effect is ideal.