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［目的］探讨肝硬变患者胆石症的发生率及其相关因素．［方法］分析３７４例肝硬变患者胆石症的 发生与民族、性别、年龄、肝硬变病因、肝功能Ｃｈｉｌｄ－ｐｕｓｈ分级以及肝功能生物化学指标之间的关系，并与 ３８６例非肝病对照组进行比较［结果］肝硬变患者胆石症的发生率高于对照组， ５０岁以上组高于 ４０岁以 下组，肝功能Ｂ级和Ｃ级组高于肝功能Ａ级组；肝硬变胆石症组血清总胆红素和总胆汁酸高于非胆石症 组，而血清白蛋白低于非胆石症组［结论］肝硬变患者常并发胆石症，并与年龄、肝功能障碍程度以及肝 功能损害造成的血清总胆红素、总胆汁酸和血清白蛋白代谢障碍等因素密切相关．
[Objective] To investigate the incidence of cholelithiasis in cirrhotic patients and its related factors. [Methods] The relationship between cholelithiasis and ethnicity, sex, age, cause of liver cirrhosis, Child-push grading of liver function and biochemical indexes of liver function were analyzed in 374 patients with cirrhosis and compared with 386 non-liver disease controls Group were compared. [Results] The incidence of cholelithiasis in cirrhotic patients was higher than that in control group, while those in patients over 50 years old were higher than those under 40 years old. The levels of liver function B and C were higher than those of patients with A grade liver cirrhosis Cholelithiasis group serum total bilirubin and total bile acids than non-cholelithiasis group, and serum albumin was lower than non-cholelithiasis group [Conclusions] Patients with cirrhosis often complicated by cholelithiasis, and with age, degree of liver dysfunction and Liver damage caused by serum total bilirubin, total bile acid and serum albumin metabolism disorders and other factors are closely related.