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对18例格林巴利综合征(Guillain-Barresyndrome,GBS)患儿血清皮质醇和TT3、TT4、TSH水平进行检测。结果表明:未用皮质激素组皮质醇水平(163.8±75.4μg/L)低于用皮质激素组(364±41μg/LP<0.05)。前者为正常水平,后者高于正常值,血清T3病人组(0.76±0.22μg/L)明显低于健康小儿组(1.10±0.62μg/L P<0.01)。3例低T3伴低T4患者中两例死亡,提示重病患儿下丘脑-垂体-甲状腺轴功能有获得性缺陷
Serum cortisol, TT3, TT4 and TSH were measured in 18 children with Guillain-Barre syndrome (GBS). The results showed that the level of cortisol in non-corticosteroid group (163.8 ± 75.4μg / L) was lower than that in corticosteroid group (364 ± 41μg / L <0.05). The former was normal and the latter was higher than normal. Serum T3 patients (0.76 ± 0.22μg / L) were significantly lower than those in healthy children (1.10 ± 0.62μg / L P <0.01). Two of the three patients with low T3 and low T4 died, suggesting that the function of the hypothalamus-pituitary-thyroid axis in critically ill children has acquired defects